We analyzed the clinical data of 31 neonates who were treated with Mechanical Ventilation in NICU at WonKwang University Hospital (WUG) from Feb. 1987 to Jan. 1989.
The results were as follows :
1) According to diagnostic categories, hyaline membrane disease was the most common in 20 cases (64.5% ), and then postasphyxia syndrome 4 cases (12.9%), apnea of prematurity 2 cases (6.5%), . Sepsis 2 cases (6.5%), in their order.
2) Twenty cases (64.5%) were born at WUH and others were born elesewhere, and male to female ratio was about 1.4: 1.
3) Premature infants below 37 wks of gestational age were 24 cases (77.4%), and hyaline membrane disease were premature in 19 cases (95.00.
4) Low birth weight infants below 2,500 gm were 26 cases (83.9%) and very low birth weight infants below 1,500 gm were 12 cases (38.7%).
In 20 cases of hyaline membrane disease, all cases were below 2,500 gm and 11 cases (55.0 %) were below 1500 gm.
5) According to selected mode of mechanical ventilation, CPAP mode ´ was used in 4 cases (12.9%) and IPPB in 27 cases (87.1%).
In 29 cases (93.6%), assist ventilation was initiated before 24 hours of age and in total duration of: mechanical ventilation, 22 cases (71.0%) were below 3 days and 4 cases (12.9%) above 7 days.
6) Complications were seen during mechanical ventilation
were intracranial hemorrhage (32.3%), infection including sepsis and pneumonia (29.0%), extrapulmonary air leaks (9.7%), in their order.
7) Total survival rate was 45.2%. For each diagnostic categories, the survival rate in hyaline membrane disease was 40.0%, postasphyxia syndrome 50.0% and apnea of prematurity 100%.
The survival rate in infants less than 999 gm was 0%, 1,000?1,499 gm 50.0%, and more than 2,500 gm 20.0%, and in infants of gestational age below 28 weeks was 0%, 29?32 weeks 57.1%, 33-36 weeks 63.6%, and above 37 weeks 42.9%.
8) Follow up observations were performed in 12 survival infants for the period of 16 months to 3 years and long term sequalae were observed in 4 cases (33.3%). They were spastic quadriplegia, seizure disorder, retinopathy of prematurity and bronchopulmonary dysplasia.
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